1. Any horny superficial growth. 2. A generalized thickening of the horny layer of the epidermis. [kerato- + G. derma, skin]
- k. blennorrhagica SYN: keratosis blennorrhagica.
- k. blennorrhagicum (blen-o-raj′i-kum) the scattered, thickened, hyperkeratotic skin lesions seen in Reiter syndrome.
- lymphedematous k. SYN: mossy foot.
- mutilating k. [MIM*124500] diffuse k. of the extremities, with the development during childhood of constricting fibrous bands around the middle phalanx of the fingers or toes that may lead to spontaneous amputation; there may be congenital deafness; autosomal dominant inheritance, caused by mutation in the gene for loricrin (LOR), a component of the epidermal differentiation complex on 1q. SYN: keratoma hereditarium mutilans, Vohwinkel syndrome.
- palmoplantar k. [MIM*148600 & MIM*244850] the occurrence of symmetrical diffuse or patchy areas of hypertrophy of the horny layer of the epidermis on the palms and soles; a group of ectodermal dysplasias of considerable variety, and either autosomal dominant or recessive inheritance. SYN: ichthyosis palmaris et plantaris, k. palmaris et plantaris, k. symmetrica, keratoma plantare sulcatum, keratosis palmaris et plantaris, tylosis palmaris et plantaris.
- punctate k. [MIM*175860] horny papules over the palms, soles, and digits that develop central plugs; seen commonly in blacks; autosomal dominant inheritance. SYN: keratoma disseminatum, keratosis punctata.
- k. symmetrica SYN: palmoplantar k..
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ker·a·to·der·ma -'dər-mə n a horny condition of the skin
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ker·a·to·der·ma (ker″ə-to-durґmə) [kerato- + derma] 1. a horny skin or covering. 2. hypertrophy of the stratum corneum of the skin; see also callus and hyperkeratosis (def. 1). Called also keratodermia.Medical dictionary. 2011.