a genetic disease in which the liver enzyme glucuronyl transferase, responsible for dealing with bilirubin, is absent. Large amounts of bilirubin accumulate in the blood, and the child becomes progressively more jaundiced. The only treatment is a liver transplant, without which life expectancy is usually less than two years.
J. F. Crigler (1919- ) and V. A. Najjar (1914- ), US paediatricians
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Crig·ler-Naj·jar syndrome (krigґlər nahґjahr) [John Fielding Crigler, Jr., American pediatrician, born 1919; Victor Assad Najjar, Lebanese-born American microbiologist, 1914–2002] see under syndrome.Medical dictionary. 2011.