parafollicular cells of the thyroid gland, which are derived from neural crest tissue. They produce calcitonin. medullary carcinoma of the thyroid has its origin in the C cells.
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1. parafollicular c's. 2. a type of cells that lack granules, such as are found in the pancreatic islets of guinea pigs. 3. chromophobe c's.Medical dictionary. 2011.