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n.
enlargement of the spleen. It most commonly occurs in malaria, schistosomiasis, and other disorders caused by parasites; in infections; in blood disorders, including some forms of anaemia and lack of platelets (thrombocytopenia); in leukaemia; and in Hodgkin's disease. See also hypersplenism.
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sple·no·meg·a·ly (sple″no-megґə-le) [spleno- + -megaly] enlargement of the spleen.Medical dictionary. 2011.