Pick disease
A form of dementia characterized by a slowly progressive deterioration of social skills and changes in personality leading to impairment of intellect, memory, and language. Dementia can be defined as a loss of intellectual abilities such as memory capacity, severe enough to interfere with social or occupational functioning. The criteria for the diagnosis of dementia include impairment of attention, orientation, memory, judgment, language, motor and spatial skills, and function. By definition,
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1. [Arnold Pick] a rare progressive degenerative disease of the brain, similar in clinical manifestations and course to Alzheimer disease but having a distinctive histopathology; cortical atrophy is confined to the frontal and temporal lobes; degenerating neurons contain globular intracytoplasmic filamentous inclusions (Pick bodies). Called also circumscribed cerebral atrophy. 2. [Ludwig Pick] Niemann-Pick d.
Medical dictionary.
2011.