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A feeling of general discomfort or uneasiness, an “out-of-sorts” feeling, often the first indication of an infection or other disease. [Fr. discomfort]
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mal·aise mə-'lāz, ma-, -'lez n an indefinite feeling of debility or lack of health often indicative of or accompanying the onset of an illness <fever, \malaise, and other flulike symptoms (Larry Thompson)>
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n.
a general feeling of being unwell. The feeling may be accompanied by identifiable physical discomfort and may indicate the presence of disease.
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mal·aise (mă-lāzґ) [Fr.] a vague feeling of bodily discomfort and fatigue.Medical dictionary. 2011.