A protein subunit of microtubules; it is a dimer composed of two globular polypeptides, α-t. and β-t.. SEE ALSO: dynein.
- t.-tyrosine ligase an enzyme that covalently links a tyrosine to the C-terminal glutamyl residue of t., coupled with the hydrolysis of ATP to ADP and orthophosphate; this is a unique posttranslational modification that may have a significant role in cytoskeletal traffic, design, and stability.
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tu·bu·lin (tooґbu-lin) a globular 55-kD protein found in all eukaryotes, existing in several isoforms; a heterodimer of α- and β-tubulin is the subunit from which microtubules are assembled.Medical dictionary. 2011.