A potent folic acid antagonist used as an antimalarial agent effective against Plasmodium falciparum; a valuable suppressant, active against the asexual erythrocytic and tissue forms; also used in the treatment of toxoplasmosis.
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py·ri·meth·amine .pī-rə-'meth-ə-.mēn n a folic acid antagonist C12H13ClN4 that is used in the treatment of toxoplasmosis and the prevention of malaria
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n.
a drug administered by mouth for the prevention and treatment of malaria, either alone or in combination with dapsone (in Maloprim); it is also used in the treatment of toxoplasmosis. Possible side-effects include loss of appetite and vomiting, and prolonged use may interfere with red blood cell production. Trade name: Daraprim.
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pyr·i·meth·amine (pir″ĭ-methґə-mēn) [USP] a folic acid antagonist, used as an antimalarial, especially for suppressive prophylaxis, and also used concomitantly with a sulfonamide in the treatment of toxoplasmosis, administered orally.Medical dictionary. 2011.