A dehydrogenated analogue of cortisone with the same actions and uses; must be converted to prednisolone before active; inhibits proliferation of lymphocytes.
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pred·ni·sone 'pred-nə-.sōnalso -.zōn n a glucocorticoid C21H26O5 that is a dehydrogenated analog of cortisone and is used as an anti-inflammatory agent, as an antineoplastic agent, and as an immunosuppressant
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pred·ni·sone (predґnĭ-sōn) [USP] a synthetic glucocorticoid derived from cortisone, administered orally as an antiinflammatory and immunosuppressant in a wide variety of disorders.Medical dictionary. 2011.