An enzyme that catalyzes the reversible reaction, α-d-glucose 1-phosphate ⇋ α-d-glucose 6-phosphate, with glucose 1,6-bisphosphate a necessary cofactor; one of the steps in glycogenolysis. SYN: glucose phosphomutase.
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phos·pho·glu·co·mu·tase -.glü-kō-'myü-.tās, -.tāz n an enzyme of both plants and animals that catalyzes the reversible isomerization of glucose-1-phosphate to glucose-6-phosphate
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phos·pho·glu·co·mu·tase (fos″fo-gloo″ko-muґtās) [EC 5.4.2.2] an enzyme of the isomerase class requiring the presence of the intermediate glucose 1,6-bisphosphate to catalyze the interconversion of glucose 1-phosphate and glucose 6-phosphate, a step in the formation and utilization of glycogen. It also catalyzes the interconversion of the 1-phosphate and 5-phosphate isomers of ribose.Medical dictionary. 2011.