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or·tho·top·ic .ȯr-thə-'täp-ik adj of or relating to the grafting of tissue in a natural position <\orthotopic transplant>
or·tho·top·i·cal·ly -i-k(ə-)lē adv
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or·tho·top·ic (or″tho-topґik) [ortho- + top- + -ic] occurring at the normal place or upon the proper part of the body; pertaining to a tissue transplant grafted into its normal place in the body.Medical dictionary. 2011.