An enzyme containing a metal (ion) as an integral part of its active structure; e.g., cytochromes (Fe, Cu), aldehyde oxidase (Mo), catechol oxidase (Cu), carbonic anhydrase (Zn).
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me·tal·lo·en·zyme mə-.tal-ō-'en-.zīm n an enzyme consisting of a protein linked with a specific metal
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me·tal·lo·en·zyme (mə-tal″o-enґzīm) an enzyme containing a tightly bound metal atom (e.g., cobalt, copper, iron, molybdenum, or zinc) as an integral part of its structure.Medical dictionary. 2011.