It is cytotoxic for all cells, but with a special affinity for bone marrow, lymphatic tissues, and rapidly proliferating cells of certain neoplasms. Used for the palliative treatment of Hodgkin disease, lymphosarcoma, and certain chronic leukemias. SYN: mustine hydrochloride.
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mech·lor·eth·amine hy·dro·chlo·ride (mek″lor-ethґə-mēn) [USP] a cytotoxic alkylating agent of the nitrogen mustard group, used in the treatment of disseminated Hodgkin disease, some non-Hodgkin lymphomas, and mycosis fungoides; administered intravenously. It is also administered intraperitoneally, intrapericardially, and intrapleurally for the palliative treatment of malignant effusions. Called also HN2 and nitrogen mustard.Medical dictionary. 2011.