2-Amino-3-methylvaleric acid; the l-amino acid found in almost all proteins; an isomer of leucine and, like it, a dietary essential amino acid.
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iso·leu·cine .ī-sō-'lü-.sēn n a crystalline essential amino acid C6H13NO2 isomeric with leucine abbr. Ile
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n.
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iso·leu·cine (Ile) (I) (i″so-looґsēn) an essential amino acid, α-amino-β-methylvaleric acid, produced by the hydrolysis of fibrin and other proteins; necessary for optimal growth in infants and for nitrogen equilibrium in human adults. See also table at amino acid. [USP] a preparation of isoleucine used as a dietary supplement.Medical dictionary. 2011.