1. Extreme incipient inflammatory reaction of the tissues to an injury. 2. The normal response of nerve or muscle to a stimulus. 3. The evocation of a normal or exaggerated reaction in the tissues by the application of a stimulus. [L. irritatio]
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ir·ri·ta·tion .ir-ə-'tā-shən n
1 a) the act of irritating
b) something that irritates
c) the state of being irritated
2) a condition of irritability, soreness, roughness, or inflammation of a bodily part
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ir·ri·ta·tion (ir″ĭ-taґshən) [L. irritatio] 1. the act of stimulating. 2. a state of overexcitation and undue sensitivity.Medical dictionary. 2011.