One of several proteins that participate in differentiation and growth. Two glycoproteins, i. A and i. B, are secreted by Sertoli cells in the testis and granulosa cells in the ovary, inhibiting FSH secretion by direct action on the pituitary. [inhibit + -in]
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in·hib·in in-'hib-ən n a glycoprotein hormone that is secreted by the pituitary gland and in the male by the Sertoli cells and in the female by the granulosa cells and that inhibits the secretion of follicle-stimulating hormone
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in·hib·in (in-hibґin) either of two glycoproteins, A and B, each composed of a common alpha subunit and one of two beta subunits; they are secreted by the gonads and found in seminal plasma and follicular fluid, and inhibit pituitary production of follicle-stimulating hormone. They also contribute to the control of gametogenesis, embryonic and fetal development, and hematopoiesis. They are members of the transforming growth factor-β superfamily of proteins, and their actions are opposed by activins, which share the same beta subunits.Medical dictionary. 2011.