Demonstration of specific antigens in tissues by the use of markers that are either fluorescent dyes or enzymes such as horseradish peroxidase.
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im·mu·no·his·to·chem·is·try (im″u-no-his″to-kemґis-tre) a technique for detecting an antigen in tissue by means of antibody that is specific for the antigen and is coupled to a label that is visible by light microscopy. Sometimes used interchangeably with immunocytochemistry. immunohistochemical adjMedical dictionary. 2011.