A semisynthetic derivative of podophyllotoxin; a mitotic inhibitor used in the treatment of refractory testicular tumors, small cell lung cancer, and other cancers.
* * *
eto·po·side .ēt-ə-'pō-.sīd, .et- n a semisynthetic podophyllotoxin derivative C29H32O13 used to treat various neoplastic diseases (as carcinoma of the lungs or testicles, AIDS-related Kaposi's sarcoma, acute myelogenous leukemia, and Ewing's sarcoma)
* * *
n.
a cytotoxic drug derived from an extract of the mandrake plant; it is inhibits topoisomerase, an enzyme involved in DNA replication. It is administered intravenously or by mouth, primarily in the treatment of bronchial carcinoma, lymphomas, and testicular tumours. Side-effects include alopecia, nausea, and marrow suppression. Trade name: Vepesid.
* * *
eto·po·side (e″to-poґsīd) [USP] a semisynthetic derivative of podophyllotoxin used as an antineoplastic in the treatment of carcinoma of the testes, lung, and bladder, lymphoma, acute myelocytic leukemia, Ewing sarcoma, and AIDS-associated Kaposi sarcoma; administered orally or intravenously.Medical dictionary. 2011.