An antineoplastic antibiotic isolated from Streptomyces peucetius; also used in cytogenetics to produce Q-type chromosome bands. SYN: adriamycin.
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doxo·ru·bi·cin .däk-sə-'rü-bə-sən n an anthracycline antibiotic with broad antineoplastic activity that is obtained from a bacterium of the genus Streptomyces (S. peucetius) and is administered in the form of its hydrochloride C27H29NO11·HCl see ADRIAMYCIN
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n.
an anthracycline anti-biotic isolated from Streptomyces peucetius caesius and used mainly in the treatment of leukaemia and various other forms of cancer. Doxorubicin acts by interfering with the production of DNA and RNA (see also cytotoxic drug). It is administered by injection or infusion and can be given as a lipid formulation (Caelyx; see liposome); side-effects include bone marrow depression, baldness, gastrointestinal disturbances, and heart damage.
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doxo·ru·bi·cin (dok″so-rooґbĭ-sin) an anthracycline (q.v.) antibiotic produced by Streptomyces peucetius var. caesius having one of the widest spectrums of antitumor activity of any antineoplastic agent.Medical dictionary. 2011.