1. A perivascular accumulation of various leukocytes seen in infectious, inflammatory, or autoimmune diseases. 2. To surround a structure with fluid or cells, as with a cuff; in chest radiography, thickening of bronchial walls on the image. [M.E. cuffe, mitten]
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cuff·ing (kufґing) the formation of a cufflike surrounding border, such as collections of leukocytes surrounding blood vessels, noted in certain viral diseases and in multiple sclerosis. Called also perivascular cuffing.Medical dictionary. 2011.