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cluster headache n a headache that is characterized by severe unilateral pain in the eye or temple, affects primarily men, and tends to recur in a series of attacks called also histamine cephalalgia, histamine cephalgia, Horton's syndrome
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a variant of migraine more common in men than in women (ratio 9:1). The unilateral pain around one eye is very severe and lasts between 15 minutes and three hours. The attacks commonly occur in the early hours of the morning but may occur eight times a day. The pain is associated with drooping of the eyelid (ptosis), a bloodshot eye, and/or excessive production of tears in the eye. The acute treatment is with antimigraine drugs (5HT1 agonists) and prophylaxis is with such drugs as verapamil, lithium, or methysergide.
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a primary headache characterized by attacks of unilateral excruciating pain over the eye and forehead, with temperature elevation, lacrimation, and rhinorrhea; attacks last from 15 minutes to about an hour and tend to occur in clusters, sometimes a few times a day for two to eight weeks followed by months or years without occurrence. Because attacks identical to the spontaneous attacks may be induced in sufferers by subcutaneous injection of histamine phosphate, it is also known as histamine cephalalgia or h. See also chronic paroxysmal hemicrania, under hemicrania. Called also Horton disease and vasomotor h.Medical dictionary. 2011.