A hydrolase that removes the amino acid at the free carboxyl end of a polypeptide chain; an exopeptidase.
- serine c. a c. of broad specificity for terminal amino acid residues of peptides; the optimum pH is 4.5 to 6.0; sensitive to diisopropyl fluorophosphate; contains a serine at the active site. SYN: acid c..
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car·boxy·pep·ti·dase -'pep-tə-.dās, -.dāz n an enzyme that hydrolyzes peptides and esp. polypeptides by splitting off sequentially the amino acids at the end of the peptide chain which contain free carboxyl groups
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car·boxy·pep·ti·dase (kahr-bok″se-pepґtĭ-dās) [EC 3.4.16–18] any exopeptidase that catalyzes the hydrolytic cleavage of the terminal or penultimate peptide bond at the C-terminal end of a peptide or polypeptide.Medical dictionary. 2011.