- congenital a. [MIM*202400] a rare disorder of blood coagulation in which little or no fibrinogen can be found in plasma because of a mutant form in one of the three fibrinogen loci. Leads to defective platelet aggregation; autosomal recessive inheritance.
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afi·brin·o·gen·emia or chiefly Brit afi·brin·o·gen·ae·mia .ā-(.)fī-.brin-ə-jə-'nē-mē-ə n an abnormality of blood clotting caused by usu. congenital absence of fibrinogen in the blood and marked by a tendency to prolonged bleeding
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afi·brin·o·gen·emia (a″fi-brin″o-jə-neґme-ə) lack of fibrinogen (coagulation factor I) in the blood; cf. hypofibrinogenemia.Medical dictionary. 2011.