The son of *Tuthmosis I by a secondary queen, Mutnefer, Tuthmosis II married *Hatshepsut, who was the Great Royal Daughter of *Tuthmosis I by his chief wife, Ahmose. This marriage apparently produced no male heir, for before his death Tuthmosis II confirmed *Tuthmosis III—the son born to him by a concubine Isis— as his successor. This did not prevent *Hatshepsut (who acted as the child's regent after Tuthmosis II's premature death) from seizing the throne in her own right. Neferure, the daughter of Tuthmosis II and *Hatshepsut, was married in childhood to *Tuthmosis III, to confirm his claim to the throne.
Despite his short reign, Tuthmosis II pursued an active military policy: a stela dating to Year 1 of his reign relates that the king overthrew an insurrection in *Nubia and also led a campaign to Palestine. At home, he contributed to the building programme in the Temple of Amun at Karnak; his funerary monuments—an undistinguished temple on the west bank at Thebes and a modest tomb with an unfinished sarcophagus in the Valley of the Kings—indicate that his reign was less illustrious than those of his father or his son.
BIBL. Edgerton, W.F. The Thutmosid succession. Chicago: 1933.
Biographical Dictionary of Ancient Egypt by Rosalie and Antony E. David
Ancient Egypt. A Reference Guide. EdwART. 2011.